The “Four Responsibilities Synergy” mechanism of seeing Party self-governance exercised fully and with rigor refers to the joint force system with the main responsibility of the Party Committee,the supervision responsibility of the commission for discipline inspection,the first responsibility of the Secretary of the Party Committee,and the “two responsibilities in one post” of the team members.The “Four Responsibilities Synergy” mechanism in colleges and universities can start with the “community of responsibility” of the “Four Responsibilities Synergy”,analyze the current situation,and construct an effective operating mechanism of the “Four Responsibilities Synergy” so as to continue to promote the healthy and rapid development of higher education.