How to improve effectiveness and pertinence of enterprise education has become an important issue in “E & I” time. college students as art majors have obvious advantages and oppor-tunities as far as entrepreneurship is concerned.Targeted entrepreneurship education can help them with double effects on their way to start entrepreneurship.According to the present entrepreneurship education and analysis of the entrepreneurial characteristics of the art students,this paper puts forward a fusion path for art majors' entrepreneurship and professional education from the perspective of curriculum construction,teaching staff and practical education.