Enhancing the party’s political leadership is driven by the goal of Party building, rejuvenating and power strengthening. It has a profound theoretical logic, distinct historical logic and important realistic logic. The principle of strengthening the party’s political leadership in the new era is: to adhere to the historical position and the objective basis of the evolving main social contradictions in the new era and the new stage; to uphold the responsibility of national rejuvenation and to deepen the political consciousness of self-revolution; and to adhere to the people’s position and system governance of the party. Overall reshaping the party organization’s advantages and improving effectiveness in fulfilling its political mission, consistently adhering to and developing democratic centralism, and cultivating high-quality and high-level party members, leading cadres and talent teams are the practical approaches to enhance the party’s political leadership in the new era.