The primary task of college teachers is to cultivate students with moral education while classroom teaching is the main means to foster virtue through education. The first lesson is significant in that “well begun is half done”. This paper focuses on the core question of “how to activate the positive effect of the first class”. First of all, it emphasizes the importance of the first class for teachers and students in universities. Secondly, given the current situation of the first class in the new semester, it finds out some space for improvement such as its meaning being neglected, formalized content, and distance between teachers and students. Finally, five promotion strategies are proposed on the basis of the first class of “Introduction to Engineering”.