The training of business talents is important in China’s higher education. As the key link for the business discipline to implement the fundamental task of establishing morality and cultivating people, the business courses-based moral value education in University of Shanghai for Science and Technology focuses on in-depth exploration into the concept of “mission driven”, the systemic ideological and political education in course teaching, characteristic development, methods of practices and quality assurance mechanism, and has achieved a lot. Based on the practical exploration, the paper puts forward suggestions to further promote the high-quality development of business courses-based moral value education in universitiesin the aspects of core elements, teacher training, teaching material, and students’ fieldwork practice.