The new productive forces represent a leap in the quality of productivity. For China to achieve a high level of self-reliance and self-improvement while fostering a new development pattern, it is necessary to prioritize technological innovation, institutional reform, industrial transformation, factor aggregation, and multi-dimensional integration. Breaking through the bottlenecks of cutting-edge technologies requires in-depth integration of the innovation chain and industrial chain with multiple regional entities of “government, industry, academia, research, and application”. Based on the existing literature, this study follows the theoretical logic of “adaptation-integration-symbiosis” to analyze the practical issues of the integrated science and technology innovation teams in the Yangtze River Delta from the perspective of new productive forces. It proposes constructing a dynamic mechanism of “node-link-network-organization” with vertical and horizontal integration, elaborates on the research framework of adaptive integration management of science and technology teams from psychological and behavioral perspectives, and explores the evolutionary path of “competitive interaction-knowledge diffusion-innovative collaboration” to enhance the innovation efficiency and capability of the integrated science and technology teams in the Yangtze River Delta region. By promoting the flow of high-quality production factors and integrating resources to establish a new innovative mechanism for collaboration and innovation, this study offers a new perspective and paradigm for commercialization of knowledge sharing and joint value creation, providing a reference for other scholars.